Lab. Spettrometria di Massa e Metabolomica – Prof. E. Baraldi, Dott. G. Giordano

Baraldi E , Lanari M, Manzoni P, Rossi GA, Vandini S, Rimini A, Romagnoli C, Colonna P, Biondi A, Biban P, Chiamenti G, Bernardini R, Picca M, Cappa M, Magazzù G, Catassi C, Urbino AF, Memo L, Donzelli G, Minetti C, Paravati F, Di Mauro G, Festini F, EInter-society consensus document on treatment and prevention of bronchiolitis in newborns and infants. Ital J Pediatr. 2014 Oct 24;40:651.523
Carraro S , Scheltema N, Bont L, Baraldi E. Early-life origins of chronic respiratory diseases: understanding and promoting healthy ageing. Eur Respir J. 2014 Dec;44(6):1682-967.636
Valerio G, Licenziati MR, Manco M, Ambruzzi AM, Bacchini D, Baraldi E , Bona G, Bruzzi P, Cerutti F, Corciulo N, Crinò A, Franzese A, Grugni G, Iughetti L, Lenta S, Maffeis C, Marzuillo P, Miraglia Del Giudice E, Morandi A, Morino G, Moro B, Perrone L,Studio Obesità Infantile della Società Italiana di Endocrinologia e Diabetologia Pediatrica. [Health consequences of obesity in children and adolescents]. Minerva Pediatr. 2014 Oct;66(5):381-4140.723
Bont L, Baraldi E , Fauroux B, Greenough A, Heikkinen T, Manzoni P, Martinón-Torres F, Nair H, Papadopoulos NG; ReSViNET. RSV--still more questions than answers. Pediatr Infect Dis J. 2014 Nov;33(11):1177-9 2,72
El Mazloum D, Moschino L, Bozzetto S, Baraldi E. Chronic lung disease of prematurity: long-term respiratory outcome. Neonatology. 2014;105(4):352-6 2,72
Da Dalt L, Putoto G, Carraro D, Gatta A, Baraldi E, Perilongo G.International child health elective for pediatric residents. Ital J Pediatr. 2014 Feb 5;40:131.523
Gucciardi A, Legnini E, Di Gangi IM, Corbetta C, Tomanin R, Scarpa M, Giordano G. A column-switching HPLC-MS/MS method for mucopolysaccharidosis type I analysis in a multiplex assay for the simultaneous newborn screening of six lysosomal storage disorders. Biomed Chromatogr. 2014 Aug;28(8):1131-91.662

 

Lab. Diagnosi e Terapie Malattie Lisosomiali – Dr.ssa R. Tomanin, Prof. M. Scarpa

 

Scarpa M , Bellettato CM, Lampe C, Begley DJ.Neuronopathic lysosomal storage disorders: Approaches to treat the central nervous system.Best Pract Res Clin Endocrinol Metab. 2015 Mar;29(2):159-714.602
Tomanin R, Zanetti A, D Avanzo F, Rampazzo A, Gasparotto N, Parini R, Pascarella A, Concolino D, Procopio E, Fiumara A, Borgo A, Frigo A, Scarpa M . Clinical efficacy of Enzyme Replacement Therapy in paediatric Hunter patients, an independent study of 3.5 years.Orphanet J Rare Dis. 2014 Sep 18;9(1):1293.958
Zancan I, Bellesso S , Costa R, Salvalaio M , Stroppiano M, Hammond C, Argenton Filocamo M, Moro E.Glucocerebrosidase deficiency in zebrafish affects primary bone ossification through increased oxidative stress and reduced Wnt/β-catenin signaling.Hum Mol Genet. 2014 Oct 176.677
Zanetti A, Tomanin R , Rampazzo A, Rigon C , Gasparotto N , Cassina M, Clementi M, Scarpa M.A Hunter Patient with a Severe Phenotype Reveals Two Large Deletions and Two Duplications Extending 1.2 Mb Distally to IDS Locus. Journal of Inherited Metabolic Disease Rep. 2014;17:13-214.138
Calias P, Banks WA, Begley D, Scarpa M , Dickson P.Intrathecal delivery of protein therapeutics to the brain: a critical reassessmentPharmacol Ther. 2014 Nov;144(2):114-227.745
Hendriksz CJ, Burton B, Fleming TR, Harmatz P, Hughes D, Jones SA, Lin SP, Mengel E, Scarpa M , Valayannopoulos V, Giugliani R; STRIVE Investigators, Slasor P, Lounsbury D, Dummer W. Efficacy and safety of enzyme replacement therapy with BMN 110 (elosulfase alfa) for Morquio A syndrome (mucopolysaccharidosis IVA): a phase 3 randomised placebo-controlled study. Journal of Inherited Metabolic Disease. 2014 Nov;37(6):979-904.138
Gucciardi A, Legnini E , Di Gangi IM, Corbetta C, Tomanin R, Scarpa M , Giordano G.A column-switching HPLC-MS/MS method for mucopolysaccharidosis type I analysis in a multiplex assay for the simultaneous newborn screening of six lysosomal storage disorders.Biomed Chromatogr. 2014 Aug;28(8):1131-91.662
Bonanni P, Volzone A, Randazzo G, Antoniazzi L, Rampazzo A, Scarpa M, Nobili L.Nocturnal frontal lobe epilepsy in mucopolysaccharidosis.Brain Dev. 2014 Oct;36(9):826-91.542
Zanetti A, Onenli-Mungan N, Elcioglu N, Ozbek MN, Kör D, Lenzini E, Scarpa M, Tomanin R . Molecular Analysis of Turkish Maroteaux-Lamy Patients and Identification of One Novel Mutation in the Arylsulfatase B (ARSB) Gene. Journal of Inherited Metabolic Disease Rep. 2014;14:1-94.138
Manara R, Concolino D, Rampazzo A, Zanetti A, Tomanin R , Faggin R, Scarpa M . Chiari 1 malformation and holocord syringomyelia in Hunter Syndrome.Journal of Inherited Metabolic Disease Rep. 2014;12:31-54.138

 

Lab. Gen. Molecolare Neurosviluppo – Prof.ssa A. Murgia

Bertossi C, Cassina M, De Palma L, Vecchi M, Rossato S, Toldo I, Donà M, Murgia A , Boniver C, Sartori S14q12 duplication including FOXG1: Is there a common age-dependent epileptic phenotype?Brain Dev. 2014 May;36(5):402-7. 1.88
Yrigollen C, Martorell L, Durbin-Johnson B, Naudo M, Genoves J, Murgia A, Polli R, Zhou L, Barbouth D, Rupchock A, Finucane B, Latham GJ, Hadd A, Berry-Kravis E, Tassone F. AGG interruptions and maternal age effect on FMR1 CGG allele stability during transmission. J Neurodev Disord. 2014;6(1):24. 3.268
Leonardi E , De Palma L, Vecchi M, Bettella E , Polli R , Sartori S, Boniver C, Murgia A. Identification of four novel PCDH19 mutations and prediction of their functional impact. Ann Hum Genet. 2014 Nov;78(6):389-98. 2.211
Yrigollen CM, Sweha S, Durbin-Johnson B, Zhou L, Berry-Kravis E, Fernandez-Carvajal I, Faradz SM, Amiri K, Shaheen H, Polli R , Murillo-Bonilla L, Silva Arevalo Gde J, Cogram P, Murgia A , Tassone F. Distribution of AGG interruption patterns within nine world populations. Intractable Rare Dis Res. 2014 Nov;3(4):153-61.

 

Lab. Neuroscienze – Prof. A. Vallesi

Vallesi AMonitoring mechanisms in visual search: an fMRI study.Brain Research, Vol. 1579, pp. 65-73.2.828
Vallesi A How developmental dissociations can inform cognitive theories.Open Access Neurosciences, Vol. 2 (1), p. 3
Della Puppa, A., De Pellegrin S., Salillas E., Grego A., Lazzarini A., Grandis M., Vallesi A., Saladini M., Scienza R., Semenza C. Functional mapping of left parietal areas involved in simple addition and multiplication. A single-case study of qualitative analysis of errors. Journal of Neuropsychology. Vol. 9 (2), pp. 330-335. 2.486
Vallesi A., Arbula, S. , Bernardis, P.Functional dissociations in temporal preparation: evidence from dual-task performance. Cognition, Vol. 130 (2), pp. 141-151.3.479
Vallesi A. , Weisblatt Y., Semenza C., Shaki S. Cultural modulations of space-time compatibility effects. Psychonomic Bulletin & Review, Vol. 21 (3), pp. 666–669.3.369
Correa A., Cona G., Arbula S., Vallesi A ., Bisiacchi P. Neural dissociation of automatic and controlled temporal preparation by transcranial magnetic stimulation. Neuropsychologia. Vol. 65 (Dec), pp. 131-136.3.302

 

Lab. Genetica Clinica – Prof. M. Clementi, Dr. L. Salviati

Nguyen TP, Casarin A, Desbats MA , Doimo M, Trevisson E , Santos-Ocaña C, NavasP, Clarke CF, Salviati L. Molecular characterization of the human COQ5 C-methyltransferase in coenzyme Q10 biosynthesis. Biochim Biophys Acta. 2014 Nov;1841(11):1628-38.4.381
Doimo M, Desbats MA, Cerqua C , Cassina M, Trevisson E, Salviati L. Genetics of coenzyme q10 deficiency. Mol Syndromol. 2014 Jul;5(3-4):156-62. 0
Tosetto E, Casarin A, Salviat i L, Familiari A, Lieske JC, Anglani F.Complexity of the 5'UTR region of the CLCN5 gene: eleven 5'UTR ends are differentially expressed in the human kidney. BMC Med Genomics. 2014 Jul 7;7:41. 2.873
Sacconi S, Wahbi K, Theodore G, Garcia J, Salviati L, Bouhour F, Vial C, Duboc D, Laforêt P, Desnuelle C. Atrio-ventricular block requiring pacemaker in patients with late onset Pompe disease.Neuromuscul Disord. 2014 Jul;24(7):648-50. 2.638
Spinazzi M, Sghirlanzoni A, Salviati L , Angelini C. Impaired copper and iron metabolism in blood cells and muscles of patients affected by copper deficiency myeloneuropathy. Neuropathol Appl Neurobiol3.927
Micale L, Augello B, Maffeo C, Selicorni A, Zucchetti F, Fusco C, De Nittis P, Pellico MT, Mandriani B, Fischetto R, Boccone L, Silengo M, Biamino E, Perria C, Sotgiu S, Serra G, Lapi E, Neri M, Ferlini A, Cavaliere ML, Chiurazzi P, Monica MD, Scarano G, Faravelli F, Ferrari P, Mazzanti L, Pilotta A, Patricelli MG, Bedeschi MF, Benedicenti F, Prontera P, Toschi B , Salviati L , Melis D, Di Battista E, Vancini A, Garavelli L, Zelante L, Merla G. Molecular analysis,pathogenic mechanisms, and readthrough therapy on a large cohort of Kabuki syndrome patients.Hum Mutat. 2014 Jul;35(7):841-50. 5.144
De Rocco D, Cerqua C , Goffrini P, Russo G, Pastore A, Meloni F, Nicchia E, Moraes CT, Pecci A, Salviati L, Savoia A. Mutations of cytochrome c identified in patients with thrombocytopenia THC4 affect both apoptosis and cellular bioenergetics
Biochim Biophys Acta. 2014 Feb;1842(2):269-74.4.381
Doimo M, Trevisson E , Airik R, Bergdoll M, Santos-Ocaña C, Hildebrandt F, Navas P, Pierrel F, Salviati L. Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency.Biochim Biophys Acta. 2014 Jan;1842(1):1-6.4.381
Trevisson E , Forzan M, Salviati L, Clementi M. Neurofibromatosis type 1 in two siblings due to maternal germline mosaicism. Clin Genet. 2014 Apr;85(4):386-9.3.931
Zanetti A, Tomanin R, Rampazzo A , Rigon C , Gasparotto N, Cassina M, Clementi M, Scarpa M. A Hunter Patient with a Severe Phenotype Reveals Two Large Deletions and Two Duplications Extending 1.2 Mb Distally to IDS Locus. Journal of Inherited Metabolic Disease Rep. 2014;17:13-214.138
Favaro A, Manara R, Pievani M, Clementi M, Forzan M , Bruson A, Tenconi E, Degortes D, Pinato C, Giannunzio V, Battista Frisoni G, Santonastaso P. Neural signatures of the interaction between the 5-HTTLPR genotype and stressful life events in healthy women. Psychiatry Res. 2014 Aug 30;223(2):157-63 2,467
Cassina M, Donà M, Di Gianantonio E, Litta P, Clementi M. First-trimester exposure to metformin and risk of birth defects: a systematic review and meta-analysis. Hum Reprod Update. 2014 Sep-Oct;20(5):656-69. 10.165
Virzì GM, Bruson A, Corradi V, Gastaldon F, de Cal M, Donà M, Cruz DN, Clementi M , Ronco C. High-resolution melt as a screening method in autosomal dominant polycystic kidney disease (ADPKD)J Clin Lab Anal. 2014 Jul;28(4):328-34.1.038
Boraska V, Franklin CS, Floyd JA, Thornton LM, Huckins LM, Southam L, Rayner ... Ophoff RA, Strengman E, van Elburg AA, Bruson A, Clementi M , Degortes D, Forzan … Estivill X, Hinney A, Sullivan PF, Collier DA, Zeggini E, Bulik CM. A genome-wide association study of anorexia nervosa. Mol Psychiatry. 2014 Oct;19(10):1085-94. 14.496
Weber-Schoendorfer C, Chambers C, Wacker E, Beghin D, Bernard N; Network of French Pharmacovigilance Centers, Shechtman S, Johnson D,Cuppers-Maarschalkerweerd B, Pistelli A, Clementi M , Winterfeld U, Eleftheriou G,Pupco A, Kao K, Malm H, Elefant E, Koren G, Vial T, Ornoy A, Meister R, Schaefer C. Pregnancy outcome after methotrexate treatment for rheumatic disease prior to or during early pregnancy: a prospective multicenter cohort study. Arthritis Rheumatol. 2014 May;66(5):1101-10. 7.764
Fallerini C, Dosa L, Tita R, Del Prete D, Feriozzi S, Gai G, Clementi M , La Manna A, Miglietti N, Mancini R, Mandrile G, Ghiggeri GM, Piaggio G, Brancati F, Diano L, Frate E, Pinciaroli AR, Giani M, Castorina P, Bresin E, Giachino D, De Marchi M, Mari F, Bruttini M, Renieri A, Ariani F Unbiased next generation sequencing analysis confirms the existence of autosomal dominant Alport syndrome in a relevant fraction of cases. Clin Genet. 2014 Sep;86(3):252-7.3.931
Paul BM, Consugar MB, Ryan Lee M, Sundsbak JL, Heyer CM, Rossetti S, Kubly VJ, Hopp K, Torres VE, Coto E, Clementi M , Bogdanova N, de Almeida E, Bichet DG, Harris PC. Evidence of a third ADPKD locus is not supported by re-analysis of designated PKD3 families. Kidney Int. 2014 Feb;85(2):383-92. 8.563

 

Lab. Immunopatologia e Biologia Molecolare del Rene – Prof.ssa L. Murer

Castagnetti M, Angelini L, Ghirardo G, Zucchetta P, Gamba P , Zanon G, Murer L ., Rigamonti WUreteral complications after renal transplant in children: timing of presentation, and their open and endoscopic managementPediatr Transplant. 2014 Mar;18(2):150-4.1.441
Cesca E, Ghirardo G, Kiblawi R, Murer L., Gamba P , Zanon GfDelayed graft function in pediatric deceased donor kidney transplantation: donor-related risk factors and impact on two-yr graft function and survival: a single-center analysisPediatr Transplant. 2014 Jun;18(4):357-62. 1.441
Negrisolo S , Centi S, Benetti E, Ghirardo G, Della Vella M, Murer L., Artifoni L SIX1 gene: absence of mutations in children with isolated congenital anomalies of kidney and urinary tractJ Nephrol. 2014 Dec;27(6):667-71.1.454
Benetti E , Caridi G, Centi S, Vella M D, Ghiggeri Gm, Artifoni L, Murer LmRNA sequencing of a novel nphs2 intronic mutation in a child with focal and segmental glomerulosclerosisSaudi J Kidney Dis Transpl. 2014 Jul;25(4):854-7.0
Vidal E, Amigoni A, Brugnolaro V, Ghirardo G, Gamba P, Pettenazzo A, Zanon Gf, Cosma C, Plebani M, Murer LNear-infrared spectroscopy as continuous real-time monitoring for kidney graft perfusionPediatr Nephrol. 2014 May;29(5):909-14.2.856
Ghirardo G, De Franceschi M, Vidal E, Vidoni A, Ramondo G, Benetti E, Motta R, Ferraro A, Zanon Gf, Miotto D, Murer LTransplant renal artery stenosis in children: risk factors and outcome after endovascular treatment.Pediatr Nephrol. 2014 Mar;29(3):461-7.2.856
Ghirardo G, Benetti E , Poli F, Vidal E, Della Vella M,Cozzi E, Murer LPlasmapheresis-resistant acute humoral rejection successfully treated with anti-c5 antibody.Pediatr Transplant. 2014 Feb;18(1):E1-5.1.441
Ferraresso M, Belingheri M, Ginevri F, Murer L ., Dello Strologo L, Cardillo M, Parodi A, Ghirardo G, Guzzo I, Innocente A, Ghio L.Three-yr safety and efficacy of everolimus and low-dose cyclosporine in de novo pediatric kidney transplantpatientsPediatr Transplant. 2014 Jun;18(4):350-6. 1.441

 

Gr. Prof. G. Basso – Lab. Tumori solidi, Linfomi – Dr.ssa L. Mussolin, Dr. P. Bonvini, Dr.ssa A. Zin

Angelica Zin , Roberta Bertorelle, Patrizia Dall’Igna, Carla Manzitti, Claudio Gambini, Gianni Bisogno, Angelo Rosolen and Rita AlaggioEpithelioid Rhabdomyosarcoma: a Clinicopathologic and Molecular Study Am J Surg Pathol. 2014 Feb;38(2):273-8.5.145
Pillon M, Aricò M, Mussolin L , Mainardi C, Giraldi E, Garaventa A, Lombardi A, Santoro N, Carraro E, d'Amore ES, Rosolen AItalian Association of Pediatric Hematology, Oncology AIEOP Non-Hodgkin Lymphoma Working Group. Mediastinal Burkitt lymphoma in childhood.Pediatr Blood Cancer. 2014 Nov;61(11):2127-8. 2.4
Schneider C, Setty M, Holmes AB, Maute RL, Leslie CS, Mussolin L , Rosolen A, Dalla-Favera R, Basso K. MicroRNA 28 controls cell proliferation and is down-regulated in B-cell lymphomas . Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8185-90. 9.6
Mussolin L , Holmes AB, Romualdi C, Sales G, D'Amore ES, Ghisi M, Pillon M, Rosolen A, Basso K. An aberrant microRNA signature in childhood T-cell lymphoblastic lymphoma affecting CDKN1B expression, NOTCH1 and growth factor signaling pathways. Leukemia. 2014 Sep;28(9):1909-12. 10.4
Gambacorti Passerini C, Farina F, Stasia A, Redaelli S, Ceccon M, Mologni L, Messa C, Guerra L, Giudici G, Sala E, Mussolin L, Deeren D, King MH, Steurer M, Ordemann R, Cohen AM, Grube M, Bernard L, Chiriano G, Antolini L, Piazza R.Crizotinib in advanced, chemoresistant anaplastic lymphoma kinase-positive lymphoma patients.J Natl Cancer Inst. 2014 Feb;106(2):djt378.13.4
Ciambotti B, Mussolin L , d'Amore ES, Pillon M, Sieni E, Coniglio ML, Ros MD, Cetica V, Aricò M, Rosolen A.Monoallelic mutations of the perforin gene may represent a predisposing factor to childhood anaplastic large cell lymphomaJ Pediatr Hematol Oncol. 2014 Aug;36(6):e359-65. 0.9

 

Gr. Prof. G. Basso – Lab. Oncoematologia Pediatrica

Paganin M , Fabbri G, Conter V, Barisone E, Polato K, Cazzaniga G, Giraldi E, Fagioli F, Aricò M, Valsecchi MG, Basso G. Postinduction Minimal Residual Disease Monitoring by Polymerase Chain Reaction in Children With Acute Lymphoblastic Leukemia. J Clin Oncol. 2014 Nov 1;32(31):3553-8. 18.428
La Starza R, Borga C, Barba G, Pierini V, Schwab C, Matteucci C, Lema Fernandez AG, Leszl A, Cazzaniga G, Chiaretti S, Basso G , Harrison CJ, Te Kronnie G , Mecucci C. Genetic profile of T-cell acute lymphoblastic leukemias with MYC-translocations.Blood. 2014 Dec 4;124(24):3577-82.10.452
Pistollato F, Louisse J, Scelfo B, Mennecozzi M, Accordi B, Basso G , Gaspar JA, Zagoura D, Barilari M, Palosaari T, Sachinidis A, Bremer-Hoffmann S. Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: Effects of CREB pathway inhibition. Toxicol Appl Pharmacol. 2014 Oct 15;280(2):378-88. 3.705
Nikolaev SI, Garieri M, Santoni F, Falconnet E, Ribaux P, Guipponi M, Murray A, Groet J, Giarin E , Basso G , Nizetic D, Antonarakis SE. Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations.Nat Commun. 2014 Aug 8;5:4654.11.47
Hrušák O, Basso G , Ratei R, Gaipa G, Luria D, Mejstříková E, Karawajew L, Buldini B, Rozenthal E, Bourquin JP, Kalina T, Sartor M, Dworzak MN; AIEOP-BFM Flow Network. Flow diagnostics essential code: a simple and brief format for the summary of leukemia phenotyping. Cytometry B Clin Cytom. 2014 Jul;86(4):288-91.2.398
Milani G, Rebora P, Accordi B , Galla L, Bresolin S , Cazzaniga G, Buldini B, Mura R, Ladogana S, Giraldi E, Conter V, Te Kronnie G , Valsecchi MG, Basso GLow PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome. Oncotarget. 2014 Jul 30;5(14):5234-45.6.359
Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, Bresolin S , Frasson C , Basso G , Guzzardo V, Fassina A, Cordenonsi M, Piccolo S. YAP/TAZ Incorporation in the β-Catenin destruction complex orchestrates the Wnt Response. Cell. 2014 Jul 3;158(1):157-70. 32.242
Masetti R, Rondelli R, Fagioli F, Mastronuzzi A, Pierani P, Togni M, Menna G, Pigazzi M , Putti MC, Basso G , Pession A, Locatelli F. Infants with acute myeloid leukemia treated according to the Associazione Italiana di Ematologia e Oncologia Pediatrica 2002/01 protocol have an outcome comparable to that of older children. Haematologica. 2014 Aug;99(8):e127-9. 5.814
Franca R, Rebora P, Athanasakis E, Favretto D, Verzegnassi F, Basso G , Tommasini A, Valsecchi MG, Decorti G, Rabusin M. TNF-α SNP rs1800629 and risk of relapse in childhood acute lymphoblastic leukemia: relation to immunophenotype.Pharmacogenomics. 2014 Apr;15(5):619-27. 3.218
Franchi N, Piccinni E, Ferro D, Basso G , Spolaore B, Santovito G, Ballarin L. Characterization and transcription studies of a phytochelatin synthase gene from the solitary tunicate Ciona intestinalis exposed to cadmium. Aquat Toxicol. 2014 Jul;152:47-56. 3.451
Tumino M, Mainardi C, Pillon M, Calore E, Gazzola MV, Destro R, Strano A, Varotto S, Gregucci F, Basso G , Messina C. Haploidentical TCR A/B and B-cell depleted hematopoietic SCT in pediatric SAA and aspergillosis.Bone Marrow Transplant. 2014 Jun;49(6):847-93.57
Bertacchini J, Guida M, Accordi B , Mediani L, Martelli AM, Barozzi P, Petricoin E 3rd, Liotta L, Milani G, Giordan M, Luppi M, Forghieri F, De Pol A, Cocco L, Basso G , Marmiroli S. Feedbacks and adaptive capabilities of the PI3K/Akt/mTOR axis in Acute Myeloid Leukemia revealed by pathway selective inhibition and phosphoproteome analysisLeukemia. 2014 Nov;28(11):2197-205.10.431
Manara E , Baron E, Tregnago C, Aveic S, Bisio V, Bresolin S, Masetti R, Locatelli F, Basso G, Pigazzi M . MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia.Blood. 2014 Jul 10;124(2):263-72. 10.452
Masetti R, Togni M, Astolfi A, Pigazzi M , Indio V, Rivalta B, Manara E , Rutella S, Basso G, Pession A, Locatelli F. Whole transcriptome sequencing of a paediatric case of de novo acute myeloid leukaemia with del(5q) reveals RUNX1-USP42 and PRDM16-SKI fusion transcripts.Br J Haematol. 2014 Aug;166(3):449-52.4.711
Torelli GF, Peragine N, Raponi S, Pagliara D, De Propris MS, Vitale A, Bertaina A, Barberi W, Moretta L, Basso G , Santoni A, Guarini A, Locatelli F, Foa' RRecognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells.Haematologica. 2014 Jul;99(7):1248-54.5.814
Pillozzi S, Accordi B , Rebora P, Serafin V, Valsecchi MG, Basso G, Arcangeli A. Differential expression of hERG1A and hERG1B genes in pediatric acute lymphoblastic leukemia identifies different prognostic subgroups. Leukemia. 2014 Jun;28(6):1352-5.10.431
Conter V, Valsecchi MG, Parasole R, Putti MC, Locatelli F, Barisone E, Lo Nigro L, Santoro N, Aricò M, Ziino O, Pession A, Testi AM, Micalizzi C, Casale F, Zecca M, Casazza G, Tamaro P, La Barba G, Notarangelo LD, Silvestri D, Colombini A, Rizzari C, Biondi A, Masera G, Basso G .Childhood high-risk acute lymphoblastic leukemia in first remission: results after chemotherapy or transplant from the AIEOP ALL 2000 studyBlood. 2014 Mar 6;123(10):1470-8.10.452
Fiocco U, Accordi B , Martini V, Oliviero F, Facco M, Cabrelle A, Piva L, Molena B, Caso F, Costa L, Scanu A, Pagnin E, Atteno M, Scarpa R , Basso G , Semenzato G, Punzi L, Doria A, Dayer JM. JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritisImmunol Res. 2014 Jan;58(1):61-93.098
Manara E, Bisio V, Masetti R, Beqiri V, Rondelli R, Menna G, Micalizzi C, Santoro N, Locatelli F, Basso G, Pigazzi M. Core-binding factor acute myeloid leukemia in pediatric patients enrolled in the AIEOP AML 2002/01 trial: screening and prognostic impact of c-KIT mutations.Leukemia. 2014 May;28(5):1132-4.10.431
Buitenkamp TD, Izraeli S, Zimmermann M, Forestier E, Heerema NA, van den Heuvel-Eibrink MM, Pieters R, Korbijn CM, Silverman LB, Schmiegelow K, Liang DC, Horibe K, Arico M, Biondi A, Basso G , Rabin KR, Schrappe M, Cario G, Mann G, Morak M, Panzer-Grümayer R, Mondelaers V, Lammens T, Cavé H, Stark B, Ganmore I, Moorman AV, Vora A, Hunger SP, Pui CH, Mullighan CG, Manabe A, Escherich G, Kowalczyk JR, Whitlock JA, Zwaan CMAcute lymphoblastic leukemia in children with Down syndrome: a retrospective analysis from the Ponte di Legno study groupBlood. 2014 Jan 2;123(1):70-7.10.452
Meissner B, Bartram T, Eckert C, Trka J, Panzer-Grümayer R, Hermanova I, Ellinghaus E, Franke A, Möricke A, Schrauder A, Teigler-Schlegel A, Dörge P, von Stackelberg A, Basso G , Bartram CR, Kirschner-Schwabe R, Bornhäuser B, Bourquin JP, Cazzaniga G, Hauer J, Attarbaschi A, Izraeli S, Zaliova M, Cario G, Zimmermann M, Avigad S, Sokalska-Duhme M, Metzler M, Schrappe M, Koehler R, Te Kronnie G, Stanulla M. Frequent and sex-biased deletion of SLX4IP by illegitimate V(D)J-mediated recombination in childhood acute lymphoblastic leukemia.Hum Mol Genet. 2014 Feb 1;23(3):590-601.6.393
Agnusdei V, Minuzzo S, Frasson C , Grassi A, Axelrod F, Satyal S, Gurney A, Hoey T, Seganfreddo E, Basso G , Valtorta S, Moresco R, Amadori A, Indraccolo S. Therapeutic antibody targeting of Notch1 in T-acute lymphoblastic leukemia xenografts.Leukemia. 2014 Feb;28(2):278-8810.431
Rampazzo E , Della Puppa A, Frasson C , Battilana G, Bianco S, Scienza R, Basso G, Persano L. Phenotypic and functional characterization of Glioblastoma cancer stem cells identified through 5-aminolevulinic acid-assisted surgery.J Neurooncol. 2014 Feb;116(3):505-13. 3.07
Lesma G., Sacchetti A., Silvani A, Bai R., Hamel E., Bortolozzi R., Basso G., VIOLA G. Hemiasterline analogues incorporating aromatic and heterocyclic type C-terminus: design, synthesis and cytotoxic evaluation. Mol Divers. 2014 May;18(2):357-73.1.896
Romagnoli, Baraldi P.G.,Lopez-Cara C., Kimatrai Salvador M.,Preti D., Aghazadeh Tabrizi M., Balzarini J., Nussbaumer P., Brancale A., Xian-Hua Fu, Jun Li, Su-Zhan Zhang R., Hamel E. Bortolozzi, Basso G., VIOLA G. Design, Synthesis and Biological Evaluation of 3,5-Disubstituted 2-Amino Thiophene Derivatives As a Novel Class of Antitumor Agents Bioorg Med Chem. 2014 Sep 15;22(18):5097-109.2.793
Bortolozzi R., VIOLA G., Porcù E ., Consolaro F., Marzano C., Pellei M., Gandin V., Basso G. A novel copper(I) complex induces ER stress-induced apoptosis in leukemia cell lines. Oncotarget. 2014 Aug 15;5(15):5978-916.359
Romagnoli R. , Baraldi P.G., Kimatrai Salvador M., Khayah M., Preti D., Aghazadeh Tabrizi M., Hamel E., Consolaro F., Basso G., VIOLA G. Design, Synthesis and Biological Evaluation of Arylcinnamide Hybrid Derivatives as Novel Anticancer Agents. Eur J Med Chem. 2014 Jun 23;81:394-407.3.447
Cosimelli B., Laneri S., Ostacolo C., Sacchi A., Severi E., Porcù E., Rampazzo E ., Moro E., Basso G., VIOLA G. Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]piridine as new inhibitors of the Wnt/β-catenin signaling. Eur J Med Chem. 2014 Aug 18;83:45-56.3.447
Porcù E. , Sipos A. Basso G ., Hamel E. Ruoli B., Stempfer V., Udvardy A., Bényei A.C., Schmidhammer H., Antus S., VIOLA G.Novel 9’-substituted-noscapines: synthesis with Suzuki cross-coupling, structure elucidation and biological evaluation. Eur J Med Chem. 2014 Sep 12;84:476-90.3.447
Romagnoli R., Baraldi PG, Kimatrai Salvador M., Prencipe .F, Bertolasi V., Cancellieri M., Brancale A., Hamel E., Castagliuolo I., Consolaro F., Porcù E., Basso G., VIOLA G. Synthesis, Antimitotic and Antivascular Activity of 1-(3',4',5'-Trimethoxybenzoyl)-3-Arylamino-5-Amino-1,2,4-Triazoles.J Med Chem. 2014 Aug 14;57(15):6795-808.5.447
Porcù E., Bortolozzi R., Basso G., VIOLA G. Recent advances on vascular disrupting agents Future Med Chem. 2014 Sep;6(13):1485-98.3.744
Dall’Acqua F., Linardi M.A., Bortolozzi R ., Clauser M., Marzocchini S., Maggi F.,Nicoletti M., Innocenti G., Basso G., VIOLA G. Natural daucane esters induces apoptosis in luekemic cells through ROS production. Phytochemistry. 2014 Dec;108:147-56. 2.547
De Martin S, Paliuri G, Belloni A, Orso G , Zanarella E, Stellin G, Milanesi O, Basso G , Ruga EM, Frasson C , Gabbia D, Perdoncin G, Palatini P, Bova S.Expression and distribution of the adrenomedullin system in newborn human thymus.PLoS One. 2014 May 15;9(5):e97592. 3.234
Lignitto L, Mattiolo A, Negri E, Persano L , Gianesello L, Chieco-Bianchi L, Calabrò ML. Crosstalk between the mesothelium and lymphomatous cells: insight into the mechanisms involved in the progression of body cavity lymphomas.Cancer Med. 2014 Feb;3(1):1-13.2.5
Schiavone M, Rampazzo E , Casari A, Battilana G, Persano L, Moro E, Liu S, Leach SD, Tiso N, Argenton F. Zebrafish reporter lines reveal in vivo signaling pathway activities involved in pancreatic cancer. Dis Model Mech. 2014 Jul;7(7):883-944.973
Della Puppa A, Gioffrè G, Gardiman MP, Frasson C, Cecchin D, Scienza R, Persano L. Intra-operative 5-aminolevulinic acid (ALA)-induced fluorescence of medulloblastoma: phenotypic variability and CD133(+) expression according to different fluorescence patterns. Neurol Sci. 2014 Jan;35(1):99-102.1.447
Baytas S. N., Inceler N., Yilmaz A., Olgac A., Menevse S., Banoglu E., Hamel E., Bortolozzi R., VIOLA G. Synthesis, biological evaluation and molecular docking studies of trans -indole-3-acryl amide derivatives as tubulin polymerization inhibitors Bioorg Med Chem. 2014 Jun 15;22(12):3096-1042.793
Bortolozzi R., von Gradowski S., Ihmels H., Schäfer K., VIOLA G. Selective Ratiometric Detection of H 2 O 2 in Water and in Living Cells with Benzo[ b ]quinolizinium Boronic Acid Derivatives Chem Commun (Camb). 2014 Aug 4;50(60):8242-56.834
Silvia Bresolin, Paola De Filippi, Claudia Cagioni, Simone Cesaro, Annamaria Di Meglio, Anna Leszl, Fiorenza Aprili, Chiara Cugno, Chiara Frasson, Marco Zecca, Cesare Danesino and Geertruyte KronnieDiscordant Disease Course in a Monozygotic Twin Pair with Juvenile Myelomonocytic LeukemiaJournal of Genetics and Genome Research 3,585
Ferraresso S, Bresolin S , Aricò A, Comazzi S, Gelain ME, Riondato F, Pession A, Zanconato F, Guzzo G, Bicciato S, Dupont S. Bargelloni L, Marconato L , Kronnie Gt , Aresu L.Epigenetic silencing of TFPI-2 in canine diffuse large B-cell lymphoma.PLoS One. 2014 Apr 2;9(4):e92707. 3.234
Cesaro S, De Filippi P, Di Meglio A , Leszl A, Donska S, Zaccaron A, Cagioni C, Galavotti R, Danesino C, Aprili F, Cugno C, te Kronnie G , Zecca M, Bresolin S.Different outcomes of allogeneic hematopoietic stem cell transplant in a pair of twins affected by juvenile myelomonocytic leukemia.Int J Hematol. 2014 Feb;99(2):208-12. 1.918

 

Lab. Neuroblastoma – Prof. G.P. Tonini

Manara E, Baron E, Tregnago C, Aveic S, Bisio V, Bresolin S, Masetti R, Locatelli F, Basso G, Pigazzi M MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemiaBlood. 2014 Jul 10;124(2):263-72.10.452
Molenaar RJ, Verbaan D, Lamba S, Zanon C , Jeuken JW, Boots-Sprenger SH, Wesseling P, Hulsebos TJ, Troost D, van Tilborg AA, Leenstra S, Vandertop WP, Bardelli A, van Noorden CJ, Bleeker FE. The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone. Neuro Oncol. 2014 Sep;16(9):1263-73.3.07
Bleeker FE, Lamba S, Zanon C , Molenaar RJ, Hulsebos TJ, Troost D, van Tilborg AA, Vandertop WP, Leenstra S, van Noorden CJ, Bardelli A. Mutational profiling of kinases in glioblastomaBMC Cancer. 2014 Sep 26;14:718. 3.362
Rihani A, Van Maerken T, De Wilde B, Zeka F, Laureys G, Norga K, Tonini GP, Coco S, Versteeg R, Noguera R, Schulte JH, Eggert A, Stallings RL, Speleman F, Vandesompele J. Lack of association between MDM2 promoter SNP309 and clinical outcome in patients with neuroblastoma. Pediatr Blood Cancer. 2014 Oct;61(10):1867-70.2.562
Rihani A, De Wilde B, Zeka F, Laureys G, Francotte N, Tonini GP , Coco S, Versteeg R, Noguera R, Schulte JH, Eggert A, Stallings RL, Speleman Vandesompele J, Van Maerken T.CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients. PLoS One. 2014 Dec 11;9(12):e114696. 3.234
Barbieri E, De Preter K, Capasso M, Chen Z, Hsu DM, Tonini GP , Lefever S, Hicks J, Versteeg R, Pession A, Speleman F, Kim ES, Shohet JM.Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastomaCancer Res. 2014 Feb 1;74(3):765-74.9.329

 

Lab. Nano Inspired Biomedicine – Dr. M. Agostini

Calandra E , Crotti S , Agostini M , Nitti D, Roverso M, Toffoli G, Marangon E, Posocco B, Traldi P . Matrix-assisted laser desorption/ionization, nanostructure-assisted laser desorption/ionization and carbon nanohorns in the detection of antineoplastic drugs. 1. The cases of irinotecan, sunitinib and 6-alpha-hydroxy paclitaxel. Eur J Mass Spectrom 1.165
Perilli L, Vicentini C, Agostini M , Pizzini S, Pizzi M, D’Angelo E , Bortoluzzi S, Mandruzzato S, Mammano E, Rugge M, Nitti D, Scarpa A, Fassan M, Zanovello P. Circulating miR-182 is a biomarker of colorectal adenocarcinoma progression.Oncotarget. 2014 Aug 30;5(16):6611-96.627
Kong A , Gupta C, Ferrari M, Agostini M , Bedin C , Bouamrani A, Tasciotti E, Azencott R. Biomarker Signature Discovery from Mass Spectrometry Data.IEEE/ACM Trans Comput Biol Bioinform. 2014 Jul-Aug;11(4):766-72.1.616
Pasto A, Serafin V, Pilotto G, Lago C, Bellio C, Trusolino L, Bertotti A, Hoey T, Plateroti M, Esposito G, Agostini M , Nitti D, Amadori A, Indraccolo S. Notch3 signaling regulates musashi-1 expression in metastatic colorectal cancer cells. Cancer Res. 2014 Apr 1;74(7):2106-18. 9.284
Agostini M , Crotti S , Bedin C , Cecchin E, Maretto I, D'Angelo E, Pucciarelli S, Nitti D.Predictive response biomarkers in rectal cancer neoadjuvant treatment. Front Biosci (Schol Ed). 2014 Jan 1;6:110-9.3.286

 

Lab. Medicina Rigenerativa – Dr.ssa M. Pozzobon, Prof. M.  Muraca

Pozzobon M, Franzin C, Piccoli M, De Coppi P.Fetal stem cells and skeletal muscle regeneration: a therapeutic approach.Front Aging Neurosci. 2014 Aug 27;6:222. 4
Pozzobon M, Piccoli M , De Coppi P . Stem cells from fetal membranes and amniotic fluid: markers for cell isolation and therapy purposes. Cell Tissue Bank. 2014 Jun;15(2):199-211. 1.24
Archacka K*, Pozzobon M *, Repele A, Rossi CA, Campanella M, De Coppi P.Culturing muscle fibers in hanging drops: a novel approach to solve an old problem.Biol Cell. 2014 Feb;106(2):72-82. 3.5
Zani A, Cananzi M, Fascetti-Leon F, Lauriti G, Smith VV, Bollini S, Ghionzoli M, D'Arrigo A, Pozzobon M, Piccoli M , Hicks A, Wells J, Siow B, Sebire NJ, Bishop C, Leon A, Atala A, Lythgoe MF, Pierro A, Eaton S, De Coppi P.Amniotic fluid stem cells improve survival and enhance repair of damaged intestine in necrotising enterocolitis via a COX-2 dependent mechanism.Gut. 2014 Feb;63(2):300-9.14.66

Lab. Meccanismi Neurodegenerazione – Dr.ssa G. Orso

Antonioli L, Giron MC, Colucci R, Pellegrini C, Sacco D, Caputi V, Orso G , Tuccori M, Scarpignato C, Blandizzi C, Fornai M.Involvement of the P2X7 purinergic receptor in colonic motor dysfunction associated with bowel inflammation in rats.PLoS One. 2014 Dec 30;9(12):e116253.3.234
De Martin S, Paliuri G, Belloni A, Orso G , Zanarella E, Stellin G, Milanesi O, Basso G , Ruga EM, Frasson C , Gabbia D, Perdoncin G, Palatini P, Bova S.Expression and distribution of the adrenomedullin system in newborn human thymus.PLoS One. 2014 May 15;9(5):e97592. 3.234
Trenti A, Grumati P, Cusinato F, Orso G, Bonaldo P, Trevisi L.Cardiac glycoside ouabain induces autophagic cell death in non-small cell lung cancer cells via a JNK-dependent decrease of Bcl-2.Biochem Pharmacol. 2014 May 15;89(2):197-209.5.009

 

Lab. Dip. Fisica e Astronomia – Prof. F. Romanato

Meneghello, Anna; Antognoli, Agnese; Sonato, Agnese; Zacco, Gabriele; Ruffato, Gianluca; Cretaio, Erica; Romanato, FilippoLabel-Free Efficient and Accurate Detection of Cystic Fibrosis Causing Mutations Using an Azimuthally Rotated GC-SPR PlatformAnal Chem. 2014 Dec 2;86(23):11773-81. 1.821
Giorgis, Valentina; Zilio, Pierfrancesco; Ruffato, Gianluca; Massari, Michele; Zacco, Gabriele; Romanato, FilippoResonance properties of thick plasmonic split ring resonators for sensing applicationsOpt Express. 2014 Nov 3;22(22):26476-86.3.488
Carli, Marta; Zilio, Pierfrancesco; Garoli, Denis; Giorgis, Valentina; Romanato, FilippoSub-wavelength confinement of the orbital angular momentum of light probed by plasmonic nanorods resonancesOpt Express. 2014 Oct 20;22(21):26302-11. 3.488
Perino, M.; Pasqualotto, E.; De Toni, A.; Garoli, D.; Scaramuzza, M.; Zilio, P.; Ongarello, T.; Paccagnella, A.; Romanato, F.Development of a complete plasmonic grating-based sensor and its application for self-assembled monolayer detectionAppl Opt. 2014 Sep 10;53(26):5969-76. 1.784
Giorgis, V.; Zilio, P.; Massari, M.; Ruffato, G.; Zacco, G.; Romanato, F.Fabrication of multiple large arrays of split ring resonators by X-ray lithographic process for sensing purposesMicroelectronic Engineering1.197
Zilio, Pierfrancesco; Parisi, Giuseppe; Garoli, Denis; Carli, Marta; Romanato, FilippoBilayer holey plasmonic vortex lenses for the far field transmission of pure orbital angular momentum light statesOpt Lett. 2014 Aug 15;39(16):4899-902. 3.292
Gazzola, E.; Brigo, L.; Zacco, G.; Zilio, P.; Ruffato, G.; Brusatin, G.; Romanato, F.Coupled SPP Modes on 1D Plasmonic Gratings in Conical MountingPlasmonics2.238
Sammito, Davide; De Salvador, Davide; Zilio, Pierfrancesco; Biasiol, Giorgio; Ongarello, Tommaso; Massari, Michele; Ruffato, Gianluca; Morpurgo, Margherita; Silvestri, Davide; Maggioni, Gianluigi; Bovo, Gianluca; Gaio, Michele; Romanato, FilippoIntegrated architecture for the electrical detection of plasmonic resonances based on high electron mobility photo-transistorsNanoscale. 2014;6(3):1390-7.7.394